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Tag Archives: Local Anaesthesia

Toxicity of Local Anaesthesia

Local Anaesthesia

Toxicity can be categorised as either local or systemic: Local toxicity includes: Infection Haematoma Local tissue damage e.g. intraneural injection Unwanted nerve block Necrosis through ischaemia from vasoconstrictor Pneumothorax (in blocks around the neck or axilla) Systemic toxicity: Cardiovascular toxicity includes: Cardiac depression – reduced BP, tachycardia, reduced cardiac output and acute cardiac dilatation Peripheral vasodilatation, except cocaine–vasoconstriction Respiratory toxicity includes: Medullary …

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Local Anaesthetic Types: Key Features

Local Anaesthesia Types

Lidocaine Type: Amide No inherent vasodilatation or vasoconstriction Can be used with vasoconstrictor e.g epinephrine Epinephrine is generally contraindicated in end arteries, for example in fingers, penis and earlobes. However, recent research suggests that 1:100,000 may be safe Infiltration normally 0.5-1.0% Small nerves normally 1% Large nerves normally 1.5% with epinephrine Painful on injection with no improvement with buffering, but improved …

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